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In the phase 3 ACHIEVE-1 trial, published in June 2025, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with
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Orforglipron, approved as Foundayo on April 1, 2026, adds another oral GLP-1 option for chronic weight management in adults with obesity or overweight plus at least one weight-related condition. The clinical relevance
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🚨New Episode: First-line Medications for Type 2 Diabetes🚨 What are the specific indications for the 3 first-line diabetes medications? 📋✓What kind of patients would be good candidates for metformin vs a GLP-1?
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