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Obesity trials are evolving 👇 New Phase 2 data (Nature Medicine, BELIEVE trial) evaluates bimagrumab ± semaglutide—and highlights a shift beyond weight loss alone. • Focus on fat vs. lean mass •
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Bimagrumab preserves lean mass and sustains fat loss during semaglutide-induced weight reduction in diet-induced obese mice
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New phase 2 data just published in Nature Medicine on bimagrumab combined with semaglutide. Swipe for the breakdown. Follow @adam_nessim for more. Source: Heymsfield et al., Nature Medicine, March 2, 2026
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New drugs for the treatment of obesity: do we need approaches to preserve muscle mass? | Reviews in Endocrine and Metabolic Disorders
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Bimagrumab plus semaglutide alone or in combination for the treatment of obesity: a randomized phase 2 trial
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Combined use of semaglutide with an investigational monoclonal antibody called bimagrumab produced significant fat mass loss while preserving lean mass, results from the phase 2b BELIEVE study found. http://ms.spr.ly/6180SLSUq
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Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism
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