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retatrutide is a novel triple agonist peptide at the glucagon receptor, GIP receptor, and GLP-1 receptor. 22-24% weight loss at 48 weeks with a similar tolerability profile to #tirzepatide. @LillyPad #medtwitter #endotwitter
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Hitting the Triple G Spot: The New Triple G Agonist for Weight Loss
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Why does GLP‐1 agonist combined with GIP and/or GCG agonist have greater weight loss effect than GLP‐1 agonist alone in obese adults without type 2 diabetes? - Jiang - 2025
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Effects of site-directed mutagenesis of GLP-1 and glucagon receptors on signal transduction activated by dual and triple agonists
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Schematic illustration of monoagonists, dual agonists and triple
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Upcoming wave of hormone-based therapies set to change field of diabetes, obesity care
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