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Gut hormones like ghrelin (↑ hunger) & GLP-1/PYY (↓ hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4
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The effects of GLP-1 family members on ghrelin. A : Dose-response curve...
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Mechanisms controlling hormone secretion in human gut and its relevance to metabolism
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