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Compounded medications are permitted by the FDA in times of shortage. That was present from 2021-2024 (tirzepatide) and 2025 (semaglutide). That has ended. The last two year grace period of continued
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The FDA has removed semaglutide injection products (GLP-1) from the shortage list, ending the temporary rule that allowed pharmacies to compound these medications, often used for weight loss. Compounded drugs are custom-made
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A study in Nature Health analyzes Reddit posts between 2019 and 2025 that mentioned semaglutide or tirzepatide and finds a spectrum of associated reported side effects extending beyond the commonly known safety
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Seattle weight loss patients fret over FDA limits on off-brand drugs
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Compounded' weight-loss drugs are a growing problem for state regulators • Stateline
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