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Research shows that weight often returns after stopping GLP-1 drugs like Ozempic and Wegovy. In the STEP-1 Extension Trial (published in Diabetes, Obesity and Metabolism), participants regained about two-thirds of the weight
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Many adults stop GLP-1 therapy within a year with low restart rates, analysis finds
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Long-Term Effects Of GLP-1 Medications: What You Should Know
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Weight Reduction with GLP-1 Agonists and Paths for Discontinuation While Maintaining Weight Loss
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Weight gain after stopping GLP-1 drugs (by Patricia Toro, MD MPH)
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Why GLP-1 Drugs Alone Aren't Enough for Sustainable Weight Loss – STAAR LABS
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GLP-1 Agonist: The Good, the Bad and the Ugly
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