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soul trial oral semaglutide Please summarize the design, population, outcomes, and safety of the SOUL trial evaluating oral semaglutide 14 mg daily in adults aged 50 years or older with type 2 diabetes and established atherosclerotic

Marsoni M251S
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Wegovy Weight Loss Injector: Effective Semaglutide Therapy Mountainside Medical Novo Nordisk's Oral Semaglutide Reduces Cardiovascular Risk by 14% in SOUL Trial Frontiers The impact of oral semaglutide on glycemic control and weight reduction: a database analysis of dosing effects in Japanese individuals with type 2 diabetes In the OASIS 4 phase 3 trial, once daily oral semaglutide at a dose of 25 mg resulted in a greater mean reduction in body weight than placebo in participants with overweight or Wegovy & Weight Loss Prescriptions in Illinois PURE Telehealth
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4.3 ★★★★★
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Mike L.
Houston, US
★★★★★ 4
Comfortable fit for slip-in fabric shoes
Size: 14, Color: Black/Black
My first experience with Marc Joseph. I typically purchase dress and casual work shoes from Florsheim and occasionally Rockport. I'm giving these four stars because the initial fit and feel appear solid. Depending on the shoe brand I wear a size 14 or 15. My feet are slightly wide but I don't alway need wide fit. These size 14 fit well with wide enough toe box. I've tried slip in shoes before and they just don't feel right. These somehow work and there is no heel slip. My only reservation is the high lip on the heel for slip-in and hope they dont catch pant hems. I gave 4 stars because I'll have to determine durability. Granted they are a light fabric shoe with a soft rubber tread. I'd like them to last for at least 6 months..and use them for business casual work wear during warm weather.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 19, 2026
C
Verified Purchase
Chris
New York, US
★★★★★ 5
Stylish and comfortable.
Size: 8 Wide, Color: Black/Black
Shoes look great and fits well. Definitely recommend pocking another pair.
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Reviewed in the United States on May 10, 2026
M
Verified Purchase
Mike
Lexington, US
★★★★★ 3
Narrow for an 11.5W
Size: 11.5 Wide, Color: Navy
Nice look and material but very narrow for a wide, had to return
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Reviewed in the United States on February 25, 2026
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Verified Purchase
elizabeth a.
Omaha, US
★★★★★ 5
Great shoe.
Size: 11.5, Color: Navy
Perfect fit. Stylish comfortable.
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Reviewed in the United States on May 2, 2026
P
Verified Purchase
phala riffel
Battle Creek, US
★★★★★ 5
Comfortable shoes
Size: 10.5, Color: Black
Fit well Look great Get compliments all the time
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Reviewed in the United States on April 3, 2026

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