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nejm Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has well-established weight-loss benefits. Cagrilintide, a long-acting analogue of the satiety hormone amylin, has shown promise for weight loss in early trials. The potential
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In patients with cardiovascular disease and overweight or obesity but no diabetes, semaglutide was superior to placebo in lowering the risk of major adverse cardiovascular events at a mean follow-up of 39.8
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💉 In a large real-world study, tirzepatide was associated with a lower incidence of major cardiovascular outcomes vs semaglutide: 📊 Composite CV outcome: 1.90% vs 2.18% (HR 0.86, p=0.01) ❤️ New-onset heart
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Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
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Patients with heart failure with preserved ejection fraction often have #obesity, a condition that is associated with a greater burden of heart failure–related symptoms, worse functional capacity, and more impaired quality of
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Despite the long-time use of cardiac glycosides in the treatment of heart failure, evidence of their potential benefit in patients with heart failure and reduced ejection fraction is limited. In a decades-old
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Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity
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