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It's wild—but true: mast cells actually have GLP-1 receptors on them. So yes, using a GLP-1 agonist for mast cell activation syndrome (MCAS) is a thing—and in some cases, it really helps
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Mast Cell Activation Syndrome (MCAS) can trigger widespread inflammation, allergies, and unexplained symptoms. GLP-1 medications, such as semaglutide and tirzepatide, may help calm things down
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